The Broken Stocks list · updated 2026-08-20
2,559 U.S. stocks down 20% or more from a 52-week high.
Falling knives, broken trends, and Watch-tier early declines. Filter by tier, sector, or ticker. Tiering is computed daily from decline depth, time-frame continuity, and decline sigma.
| Tier | Ticker | Company | Decline | Sigma | TFC | Days | Price | Trigger |
|---|---|---|---|---|---|---|---|---|
| Red List |  UPB |
Upstream Bio, Inc. · Healthcare | -79.7% | 3.0σ | 4/5 | 218d | $6.85 | Depth |
| Red List |  KRRO |
Korro Bio, Inc. · Healthcare | -76.8% | 2.3σ | 2/5 | 308d | $12.96 | Depth |
| Red List |  WVE |
Wave Life Sciences Ltd. · Healthcare | -75.8% | 3.9σ | 3/5 | 254d | $5.25 | Depth |
| Red List |  MLTX |
MoonLake Immunotherapeutics · Healthcare | -74.7% | 6.4σ | 1/5 | 328d | $15.87 | Depth |
| Red List |  EYPT |
EyePoint, Inc. · Healthcare | -71.8% | 3.8σ | 3/5 | 255d | $5.39 | Depth |
| Red List |  OLMA |
Olema Pharmaceuticals, Inc. · Healthcare | -69.9% | 3.6σ | 3/5 | 247d | $10.90 | Depth |
| Red ListRecovering |  DOCS |
Doximity, Inc. · Healthcare | -66.1% | 4.6σ | 3/5 | 325d | $25.94 | Depth |
| Red ListRecovering |  LYEL |
Lyell Immunopharma, Inc. · Healthcare | -65.9% | 3.1σ | 2/5 | 241d | $15.33 | Depth |
| Red ListRecovering |  EMBC |
Embecta Corp. · Healthcare | -64.9% | 0.8σ | 4/5 | 337d | $5.46 | Depth |
| Red List |  OPRX |
OptimizeRx Corporation · Healthcare | -64.4% | 2.1σ | 2/5 | 297d | $7.93 | Depth |
| Red List |  SPRY |
ARS Pharmaceuticals, Inc. · Healthcare | -63.5% | 2.8σ | 3/5 | 364d | $5.50 | Depth |
| Red ListRecovering |  PHR |
Phreesia, Inc. · Healthcare | -63.4% | 2.8σ | 4/5 | 357d | $12.00 | Depth |
| Red List |  BIOA |
BioAge Labs, Inc. · Healthcare | -62.7% | 3.9σ | 3/5 | 45d | $9.69 | Depth |
| Red ListRecovering |  OCS |
Oculis Holding AG · Healthcare | -61.9% | 2.4σ | 3/5 | 101d | $13.12 | Depth |
| Red List |  DNA |
Ginkgo Bioworks Holdings, Inc. · Healthcare | -60.4% | 4.1σ | 2/5 | 316d | $6.96 | Depth |
| Red List |  ATEC |
Alphatec Holdings, Inc. · Healthcare | -60.1% | 3.0σ | 4/5 | 224d | $9.29 | Depth |
| Red List |  AHCO |
AdaptHealth Corp. · Healthcare | -59.9% | 5.8σ | 0/5 | 108d | $5.39 | Depth |
| Red List |  SMMT |
Summit Therapeutics Inc. · Healthcare | -58.6% | 5.1σ | 3/5 | 359d | $12.43 | Depth |
| Red List |  PODD |
Insulet Corporation · Healthcare | -58.6% | 2.9σ | 4/5 | 273d | $146.95 | Depth |
| Red ListRecovering |  INSP |
Inspire Medical Systems, Inc. · Healthcare | -58.3% | 2.1σ | 5/5 | 253d | $61.27 | Depth |
| Red List |  QDEL |
QuidelOrtho Corporation · Healthcare | -58.3% | 3.3σ | 3/5 | 216d | $14.85 | Depth |
| Red List |  NTLA |
Intellia Therapeutics, Inc. · Healthcare | -56.0% | 1.8σ | 2/5 | 304d | $12.44 | Depth |
| Red List |  CING |
Cingulate Inc. · Healthcare | -55.2% | 2.5σ | 2/5 | 156d | $5.33 | Depth |
| Red List |  BSX |
Boston Scientific Corporation · Healthcare | -54.9% | 3.2σ | 5/5 | 345d | $49.37 | Depth |
| Red ListRecovering |  ARCT |
Arcturus Therapeutics Holdings · Healthcare | -54.5% | 1.6σ | 2/5 | 303d | $10.99 | Depth |
| Red List |  RXST |
RxSight, Inc. · Healthcare | -53.9% | 4.4σ | 5/5 | 252d | $6.09 | Depth |
| Red List |  TRDA |
Entrada Therapeutics, Inc. · Healthcare | -53.8% | 1.9σ | 2/5 | 106d | $7.60 | Depth |
| Red ListRecovering |  ALNY |
Alnylam Pharmaceuticals, Inc. · Healthcare | -53.7% | 2.9σ | 3/5 | 304d | $229.30 | Depth |
| Red List |  ZTS |
Zoetis Inc. · Healthcare | -53.2% | 2.5σ | 5/5 | 365d | $75.02 | Depth |
| Red List |  PHAT |
Phathom Pharmaceuticals, Inc. · Healthcare | -53.0% | 5.1σ | 4/5 | 240d | $8.60 | Depth |
| Red List |  ALGS |
Aligos Therapeutics, Inc. · Healthcare | -53.0% | 1.9σ | 2/5 | 248d | $6.44 | Depth |
| Red ListRecovering |  ADMA |
ADMA Biologics Inc · Healthcare | -52.3% | 2.0σ | 5/5 | 251d | $9.76 | Depth |
| Red List |  CRBP |
Corbus Pharmaceuticals Holdings · Healthcare | -52.1% | 3.2σ | 2/5 | 304d | $9.84 | Depth |
| Red List |  STRO |
Sutro Biopharma, Inc. · Healthcare | -51.7% | 4.5σ | 1/5 | 97d | $21.17 | Depth |
| Red ListRecovering |  WGS |
GeneDx Holdings Corp. · Healthcare | -51.7% | 1.5σ | 4/5 | 261d | $82.62 | Depth |
| Red List |  KROS |
Keros Therapeutics, Inc. · Healthcare | -51.4% | 2.3σ | 2/5 | 255d | $10.95 | Depth |
| Red ListRecovering |  HIMS |
Hims & Hers Health, Inc. · Healthcare | -51.2% | 1.5σ | 4/5 | 309d | $31.86 | Depth |
| Red List |  PRCT |
PROCEPT BioRobotics Corporation · Healthcare | -51.1% | 2.5σ | 3/5 | 352d | $20.74 | Depth |
| Red ListRecovering |  JANX |
Janux Therapeutics, Inc. · Healthcare | -51.1% | 1.2σ | 4/5 | 267d | $17.28 | Depth |
| Red List |  CLPT |
ClearPoint Neuro Inc. · Healthcare | -49.5% | 1.2σ | 3/5 | 315d | $15.19 | Depth |
| Red List |  CRVS |
Corvus Pharmaceuticals, Inc. · Healthcare | -46.8% | 3.3σ | 2/5 | 209d | $14.33 | Depth |
| Red List |  MLYS |
Mineralys Therapeutics, Inc. · Healthcare | -46.0% | 5.2σ | 4/5 | 281d | $25.75 | Depth |
| Red List |  CUE |
Cue Biopharma, Inc. · Healthcare | -45.9% | 4.0σ | 1/5 | 41d | $24.61 | Depth |
| Red List |  VNDA |
Vanda Pharmaceuticals Inc. · Healthcare | -45.9% | 1.8σ | 2/5 | 163d | $5.38 | Depth |
| Red List |  COLL |
Collegium Pharmaceutical, Inc. · Healthcare | -45.8% | 4.9σ | 3/5 | 234d | $27.54 | Depth |
| Red ListRecovering |  CRMD |
CorMedix Inc. · Healthcare | -45.0% | 1.9σ | 2/5 | 356d | $8.23 | Depth |
| Red List |  VERA |
Vera Therapeutics, Inc. · Healthcare | -44.2% | 4.3σ | 2/5 | 239d | $31.26 | Depth |
| Red ListRecovering |  VTYX |
Ventyx Biosciences, Inc. · Healthcare | -44.0% | — | 0/5 | 226d | $14.00 | Depth |
| Red List |  GLUE |
Monte Rosa Therapeutics, Inc. · Healthcare | -42.6% | 5.8σ | 3/5 | 224d | $14.78 | Depth |
| Red List |  SGRY |
Surgery Partners, Inc. · Healthcare | -42.2% | 5.4σ | 3/5 | 364d | $13.94 | Depth |
| Red List |  AORT |
Artivion, Inc. · Healthcare | -42.0% | 2.8σ | 3/5 | 246d | $27.98 | Depth |
| Red ListRecovering |  TMDX |
TransMedics Group, Inc. · Healthcare | -41.8% | 1.4σ | 3/5 | 261d | $90.85 | Depth |
| Red ListRecovering |  SLNO |
Soleno Therapeutics, Inc. · Healthcare | -41.3% | — | 5/5 | 407d | $53.01 | Depth |
| Red List |  PAHC |
Phibro Animal Health Corporatio · Healthcare | -41.2% | 4.9σ | 0/5 | 129d | $35.18 | Depth |
| Red List |  INSM |
Insmed Incorporated · Healthcare | -41.2% | 1.2σ | 3/5 | 261d | $125.09 | Depth |
| Red List |  OFIX |
Orthofix Medical Inc. · Healthcare | -41.1% | 4.8σ | 3/5 | 289d | $10.00 | Depth |
| Red ListRecovering |  PRGO |
Perrigo Company plc · Healthcare | -40.9% | 0.6σ | 3/5 | 363d | $13.70 | Depth |
| Red ListRecovering |  WAY |
Waystar Holding Corp. · Healthcare | -40.1% | 1.0σ | 4/5 | 345d | $24.84 | Depth |
| Red List |  CELC |
Celcuity Inc. · Healthcare | -40.0% | 1.7σ | 2/5 | 108d | $90.57 | Depth |
| Red List |  RARE |
Ultragenyx Pharmaceutical Inc. · Healthcare | -36.5% | 4.5σ | 5/5 | 255d | $25.32 | TFC |
| Red List |  INBX |
Inhibrx Biosciences, Inc. · Healthcare | -36.1% | 1.4σ | 3/5 | 120d | $99.15 | Depth |
| Red List |  STAA |
STAAR Surgical Company · Healthcare | -35.7% | 3.5σ | 2/5 | 98d | $23.07 | Depth |
| Red List |  TDOC |
Teladoc Health, Inc. · Healthcare | -34.4% | 4.5σ | 2/5 | 35d | $6.49 | Depth |
| Red ListRecovering |  NAMS |
NewAmsterdam Pharma Company N.V · Healthcare | -34.2% | 4.6σ | 1/5 | 101d | $27.81 | Depth |
| Red ListRecovering |  QTTB |
Q32 Bio Inc. · Healthcare | -32.7% | 2.4σ | 0/5 | 37d | $15.86 | Depth |
| Red List |  TNGX |
Tango Therapeutics, Inc. · Healthcare | -31.6% | 6.5σ | 1/5 | 64d | $23.52 | Depth |
| Red ListRecovering |  VCYT |
Veracyte, Inc. · Healthcare | -31.4% | 5.5σ | 2/5 | 51d | $41.79 | Depth |
| Red List |  BKD |
Brookdale Senior Living Inc. · Healthcare | -30.9% | 8.8σ | 2/5 | 184d | $11.81 | Sigma |
| Red List |  AGL |
agilon health, inc. · Healthcare | -30.3% | 2.9σ | 3/5 | 34d | $92.73 | Depth |
| Red List |  PRVA |
Privia Health Group, Inc. · Healthcare | -26.4% | 8.1σ | 4/5 | 35d | $21.20 | Sigma |